As populations live longer but not always healthier, understanding the biology of aging is essential to extend healthspan, reduce age-related disease burdens, and prepare for the profound social and economic impacts of global aging.
The Science Brief first walks through a definition of aging, outlining several biological processes that are commonly associated with it such as cellular, genetic, systemic, and immune. Afterwards, the Brief discusses the field of Geroscience and the strategies associated with delaying, preventing, alleviating, or treating disorders linked to the aging process.
After discussing breakthroughs in the field of Geroscience, including the fields of senolytic drugs, epigenetic reprogramming, and base editing, the Brief concludes with considerations for the UN System such as:
- Social and economic burdens
- Environmental considerations
- Public knowledge and awareness
- Inequalities
- Military applications
Geroscience has enormous implications, not only for the health sector, but also for our global economy and sustainable development goals.
